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Successful biomarkers should move systematically and seamlessly through specific R&D “modules” - from early discovery to clinical validation. NBDA’s end-to-end systems approach is based on working with experts from all affected multi-sector stakeholder communities to build an in-depth understanding of the existing barriers in each of these “modules” to support decision making at each juncture....
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Bypass the genomic biomarker discovery and validation stage and focuses straight away on biomarkers that are detectable in the blood stream. There have been many promising biomarkers been discovered in biopsies and tissues that never translated in biomarkers that are detectable in the blood stream. This was always due to dilution effects from and markers are not sufficiently expressed on the...
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Early cancer detection by cancer biomarker is an exciting field. In addition to genetic biomarker, multiple types of cancer biomarkers have been identified. The site attempts at educating visitors on cancer biomarkers. Cancer biomarkers can be detected using various absorbance and fluorescence...
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NMR (Nuclear Magnetic Resonance) spectroscopy has proven to be a sophisticated method for the structural analysis of organic compounds at the atomic level. It has been widely applied in a broad range of research studies, especially metabolomic analyses, based on its robustness and easy processing...
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Banyan Biomarkers, Inc. is creating the first blood test to diagnose traumatic brain injury (TBI). Currently, there is no objective test that exists to detect the presence and severity of brain trauma. Banyan Biomarkers' research has identified unique and proprietary biomarkers present in the...
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The vision of the Biomarker Factory is to bring biomarker discoveries to clinical practice by the identification of biomarkers that address medical needs and to develop and commercialize diagnostic tests that have a significant impact in healthcare decisions for physicians and their patients.
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From Boehringer Ingelheim Oncology, information on biomarker testing in advanced non small cell lung cancer (NSCLC). Biopsying Physicians Collection of sufficient tissue by pulmonologists, interventional radiologists, thoracic surgeons, and other physicians who perform biopsies is a critical step in the biomarker testing process in NSCLC. Access more information designed for physicians who...
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This website provides information about the Thermo Scientific biomarker procalcitonin (PCT) and its utilization in clinical practice. Procalcitonin (PCT) is an innovative and highly specific marker for the diagnosis of clinically relevant bacterial infections and sepsis. Procalcitonin (PCT) supports early diagnosis and clinical decision making which could direct an effective therapy at the...
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Simpkins and colleagues suggest that the correlation found between MSI, MLH1 expression, and MLH1 promoter methylation shows that MLH1 plays an important role in the development of endometrial tumors. However, this research is in direct contrast to some other studies. The scientists do agree, however, that epigenetic gene silencing is most likely responsible for the defective repair of DNA...
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Kaposi sarcoma is cancer where cells lining lymphs or blood vessels. It is marked by formation of black or purple colored lesions on skin or soft tissues. They usually appear on face and legs. These lesions are painful and swells. It is also possible to have such lesions/ tumors on soft tissues like mouth, lungs, digestive track or lymph nodes. There are different forms of Kaposi Sarcoma that...
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Find out more about OGT and our innovative genetics research solutions by visiting our website. Visit Oxford Gene Technology today. The complete array solution for clinical genetics research, including accurate and sensitive products and fully accredited service options. Hear Dr Tracey Lewis (ARUP Laboratories, USA) discuss the importance of single-exon CNV changes in a variety of genetic...
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Biomarker pipeline is a National Institute for Health Research (NIHR) applied programme in renal and liver diseases. The aim of the programme is to advance the progression of promising biomarkers into clinical trials within the NHS through rapid translation and evaluation of existing biomarker research programmes. The programme also aims to develop a thorough approach to the development of new...
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ACS Biomarker recently opened a new lab specifically equipped with highly-advanced infrastructure for conducting large-scale miRNA validation studies. Through its collaborations ACS Biomarker has access to a large number of cardiovascular cohorts. The validation phase yielded a series of miRNAs adding substantial diagnostic and prognostic value to established protein markers for conditions such...
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Has been awarded a Phase II SBIR to develop an assay for pain. We were successful in our biomarker discovery experiments and hope to make a difference in the lives of the 100 million Americans affected by chronic pain. The life science industry needs biomarker information to develop products that can treat, cure or diagnose human disease. As a service to research groups, we offer assisted and...
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The Neurophysiological Biomarker Toolbox (NBT) is an open source Matlab toolbox for the computation and integration of neurophysiological biomarkers. NBT offers a pipeline from data storage to statistics including artefact rejection, signal visualization, biomarker computation, and statistical testing. NBT allows for easy implementation of new biomarkers, and incorporates an online wiki that...
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