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Bypass the genomic biomarker discovery and validation stage and focuses straight away on biomarkers that are detectable in the blood stream. There have been many promising biomarkers been discovered in biopsies and tissues that never translated in biomarkers that are detectable in the blood stream. This was always due to dilution effects from and markers are not sufficiently expressed on the...
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1
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Successful biomarkers should move systematically and seamlessly through specific R&D “modules” - from early discovery to clinical validation. NBDA’s end-to-end systems approach is based on working with experts from all affected multi-sector stakeholder communities to build an in-depth understanding of the existing barriers in each of these “modules” to support decision making at each juncture....
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2
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Discovery of “Short Peptide” Cancer Biomarkers Conventional two-dimensional polyacrylamide gel electrophoresis (“2D-PAGE”), first developed in 1975 by O’Farrell, remains the standard method used to detect cancer biomarkers. However, one of the most significant disadvantages of 2D-PAGE is that it...
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3
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Has been awarded a Phase II SBIR to develop an assay for pain. We were successful in our biomarker discovery experiments and hope to make a difference in the lives of the 100 million Americans affected by chronic pain. The life science industry needs biomarker information to develop products that...
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4
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We are experts in high-resolution metabolomics and big data pattern recognition. We provide metabolite profiling and bioinformatic discovery tools. Sandra Trenkamp, PhD, is an expert in metabolomics, biochemistry and microbiology with over ten years experience. She gained her skills at the...
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5
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Software for liquid chromatography / mass spectrometry data processing and analysis, in the fields of proteomics, metabolomics, glycoproteomics. BioAnalyte's vendor-neutral software facilitates high-speed interpretation of proteomics and metabolomic data to dramatically improve research accuracy and productivity. Most of our customers have hit a bioinformatic stumbling block: too much raw data,...
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6
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